The invention relates to an LED light tube with a plug-in drive, comprising: - An LED light tube body with a lamp housing and an internal lamp board, where one end of the lamp board has a drive interface, and the corresponding end of the housing has a plug-in cavity. - A drive mechanism with a housing assembly and an internal drive component, where one end of the drive component has a first plug-in part. The first plug-in part and drive interface are detachably connected, and the housing assembly matches the plug-in cavity for detachable connection. The invention allows quick replacement or upgrading of the drive component, improving adaptability and flexibility. (Note: Figures and references to them are retained as placeholders since actual images are not provided. (Most Illustrative Figure: Fig1)